The total distance door to door is a hair under 700 miles to Knoxville, and another 100 miles to Blairesville. I can stretch my CBR's gas tank to 180 miles, but I prefer to stop every hour or so to stretch my legs, and every other hour to fill up with gas (usually about every 130 miles) . I am figuring on 6 gas stops and another 6 rest stops.
My luggage consists of a Gears navigator tail bag, a 30liter magnetic tailbag, and a home-made tool container tube. Really, its a good setup, kinda hard to get my leg between the tail and tank bags, but once on the bike they both are great places to rest against when I get tired, and the tankbag leaves enough room to rest my elbow comfortably.
I keep all my toys (ipod, cell, camera) in the tankbag, as well as whatever I need to be easily accessible during the ride, drink, food, wallet, money, as well as directions and other necessary small items. All my electronics run off the cig lighter I have buried in my dash and a spliter I hide in the tankbag.